It is practical knowledge in the sense that we know why some parts of the world are inherently risky to live in. Even though volcanic eruptionis, earthquakes and tsunamis are difficult to predict, it makes sense to have building codes and emergency plans that take this into account.
It is science’s response to the beliefs that natural catastrophes (volcanism, earthquakes and tsunamis) are divine punishments for the evil ways of some individuals.
Even if you will never use or apply this knowledge, knowing about the theory of plate tectonics gives you a current scientific perspective on what we know about the natural world.
It is a good example of how scientific theories proceed by trying to fit several observations into a coherent explanation.
Learning about the observations that needed to be made and explained for the theory to win over scientists helps caution you against people who adopt belief systems without questioning the myths told to them, or those who try to profit from ignorance of how nature actually works.
When it is well taught, it should convince you that, like any scientific theory, plate tectonics is a “work in progress”. New discoveries continue to be made, and it takes creative and logical thinking, debate and a quest for more observations in order to determine which ones prove or challenge the current theory and which ones may lead to its refinement.
The answer is <span>c. Cold and flu season occurs when the weather is cold, so there must be a connection.
Even though choices a. and b. could make sense, nothing in Joel's research implies the connection between the choices and cold. Therefore, this leaves choice c. as the right one. If cold and flu season occurs</span><span> when the weather is cold, there must be a connection between cold and cold weather.</span>
Answer:
Abstract
Down syndrome (DS) is associated with aberrations in genetic, morphological, biochemical and physiological characteristics. A number of genes located on human chromosome 21 (HSA21) encode proteins which are thought to be involved in numerous metabolic pathways, e.g., phosphofructokinase, cystathionine β-synthase etc. Perturbations of the metabolic pathways may lead to altered drug metabolism in DS individuals. We present a review of metabolic aberrations linked to HSA21 genes in DS. We particularly focus on drug disposition, efficacy, sensitivity and toxicity of anti-leukaemic agents including methotrexate, glucocorticoids, anthracyclines and cytarabine in DS leukaemia. The different outcomes of therapy due to differential drug response, varied drug toxicity and treatment related mortality in DS leukaemia is a subject of much research and speculation. Altered drug response in DS individuals may stem from differences in pharmacokinetics, pharmacodynamics and pharmacogenetics. Further large-cohort studies in different age groups dissecting metabolic and molecular pathways involved in drug response may increase our understanding in this regard and stipulate pharmacotherapies in DS.
Cells need oxygen to break glucose to produce Energy required for doing several functions.
