Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Answer:
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Explanation:
in the body the blood vessels always stay in tack and they can never get old.
Answer:
An appropriate goal statement for Impaired swallowing is that the patient will not exhibit any signs or symptoms of aspiration during this hospitalization (e.g., lungs clear, respiratory rate within normal range for patient). Consuming 50% of meals and gaining weight are appropriate goals for Imbalanced nutrition: less than body requirements
Answer: Discus immune response to a pathogen through the oral (oral-anus) and respiratory route Discus immune response to a pathogen through the oral (oral-anus) and respiratory route Expert Answer The body is resistant to various pathogens through passive and active immunity.
Explanation: Periodontal pathogens may also present differences in their ability to induce immune responses from the host; thus, we evaluated the effects of various oral bacteria on the expression of AMPs and IL-8 by gingival epithelial cells.
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Answer:
Your chances of performing successful First Aid increase dramatically if more than one person is involved. Be sure to seek assistance from by standers, even if they are not certified. If the victim refuses first aid, call 911 and stay with the victim until help arrives.
