Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
Well, the range is more limited. Let's say if you tried listening to Denver radio all the way in Texas, you wouldn't be able to listen to it.
Another one is that other electromagnetic waves with similar frequencies can interfere with each other
bam...easy...............
Answer:
B. The burning of fossil fuels released greenhouse gases into the atmosphere causing the planet to get warm.
Explanation:
Answer:
The process in which glucose react with oxygen to provide energy and carbon dioxide and water is called <em><u>Cellular</u></em><em><u> </u></em><em><u>respiration</u></em><em><u> </u></em><em><u>.</u></em>
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<em><u>MORE</u></em><em><u> </u></em><em><u>TO</u></em><em><u> </u></em><em><u>KNOW</u></em><em><u> </u></em></h2>
- Glucose break down into 3 carbon molecule pyruvate .
- The energy produced is used to synthesis ATP which is a power house of cell.
- Cellular takes place in Mitochondria . It is an organelle in cell
- ATP is adenosine triphosphate
- ATP is utilised in maintained function of cell, synthesise protein and other works
