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statuscvo [17]
3 years ago
9

Suppose that a strain of bacteria lacks a key biochemical used in purine synthesis. Complete all the statements about purine syn

thesis in these bacteria.
1) _________(phosphoribosyl amine / glycinamide ribonucleotide / formylglycinamide ribonucleotide) will accumulate in bacteria that lack glycine. The atoms of glycine form part of both ring structures.

2) The intermediate _________(formylglycinamide ribonucleotide / glycinamide ribonucleotide / N10-formyltetrahydrofolate) will build up in the absence of tetrahydrofolate. N10‑Formyltetrahydrofolate donates _________(a phosphate group / an amino group / a formyl group) to the substrate.

3) _________(formylglycinamide ribonucleotide / glycinamide ribonucleotide / formylglycinamidine ribonucleotide) will accumulate in the absence of glutamine. Glutamine donates _________(an amino group / a phosphate group / a formyl group).

4) The intermediate _________(fumarate / carbamoyl phosphate / carboxyaminoimidazole ribonucleotide / carbamoyl aspartate) will accumulate when aspartate is lacking. Aspartate donates _________(a phosphate group / a formyl group / an amino group).
Biology
1 answer:
olga55 [171]3 years ago
8 0

Answer:

1. <u>Phosphoribosyl</u> amine

2. <u>glycinamide ribonucleotide (GAR), a formyl group</u>

3. F<u>ormylglycinamide ribonucleotide (FGAR), an amino group</u>

4. C<u>arboxyaminoimidazole ribonucleotide (CAIR), an amino group.</u>

Explanation:

1. <u>Phosphoribosyl</u> amine will accumulate in bacteria that lack glycine.

2. The intermediate <u>glycinamide ribonucleotide (GAR)</u> will build up in the absence of tetrahydrofolate.

N10‑Formyltetrahydrofolate donates <u>a formyl group</u> to the substrate

3. F<u>ormylglycinamide ribonucleotide (FGAR) </u>will accumulate in the absence of glutamine.

Glutamine donates <u>an amino group</u>

4.<u> </u>The intermediate <u>carboxyaminoimidazole ribonucleotide (CAIR)</u> will accumulate when aspartate is lacking.

Aspartate donates <u>an amino group.</u>

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