Which of the following is/are true regarding observed effects of pH on enzyme activity and rate, and the underlying causes of th
ese effects? A. The active site of an enzyme can change shape and overall charge when pH is not optimal, possibly reducing the enzyme's activity
B. All enzymes exhibit their fastest rate of reaction at an approximate physiological pH of 7.4, as all organisms □ maintain a pH range very close to this in order to avoid alkalosis or acidosis. °
C. Most enzymes will display the same reaction rate across a broad range of pH levels due to the flexibility of the active site.
D. The rate of an enzyme-catalyzed reaction will slow down when outside the optimal pH range of the enzyme.
Since living organisms function within a narrow range of pH, enzymes also are tailored to function at that physiological pH outside which the function of the enzyme is heavily impaired due alkalosis or acidosis.
