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The proximal tubule fluid is more hyperosmotic than the renal cortex, but this does not influence what is causing the acid-base disruption.
<h3>How does hyperosmotic work?</h3>
In the extracellular space, the first drop in temperature results in the formation of crystals, which creates a hyperosmotic environment that draws water out of the cells and causes them to contract. Organelles & biological membranes are damaged as a result of inner crystal formation as the temperature drops.
<h3>What transpires inside a hyperosmotic environment to a cell?</h3>
A cell submerged in a 10% dextrose hyperosmotic , osmotic pressure solution would initially lose area as water departs and then start gaining proportion as glucose is delivered through into cell as moisture follow by osmosis. This is because water crosses cell surfaces more quickly than solutes do.
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