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Alexxandr [17]
3 years ago
8

in an experiment, you mutate the retinoblastoma gene such that its gene product behaves as if hyperphosphorylated. the result wo

uld be a _____________ association between rb and e2f, with __________ transcription of genes necessary for dna replication.
Biology
1 answer:
lakkis [162]3 years ago
3 0

Answer:

1. Weaker

2. Continuous

Explanation:

A tumor suppressor gene codes for retinoblastoma protein (pRb). The retinoblastoma protein binds to transcription factor E2F when DNA damage is detected. The E2F bound to pRb can not stimulate expression of genes that code for proteins required during the process of DNA synthesis. The cell can not enter the S phase.

On the other hand, when the retinoblastoma protein is phosphorylated by cyclin E-CDK2, E2F transcription factor is free to stimulate the expression of genes required for DNA synthesis and the cell proceeds from G1 to S phase.  

When the mutated retinoblastoma gene code for a protein that serves as phosphorylated protein, it will not be able to bind strongly with E2F and there would be continuous expression of genes required for S phase.  

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You are conducting a case control study to determine if an association exists between melanoma and indoor tanning. From a statew
Aleksandr-060686 [28]

Answer:

a. Odds ratio = 1.58

b.  Inasmuch the odds ratio is greater than 1, this means that higher odds of melanoma exist in people exposed to indoor tanning, than in those not exposed to indoor tanning

Explanation:

For case  study                                                  

Let 'a'  represent the total population of people with melanomia = 696                                                      

Let 'b' represent the total number of people with melanomia exposed to indoor tanning  =  1107 – 696 = 411 people

For  control study

Let 'c' represent the total population = 1500

Let 'd' represent the total number of people not exposed to indoor tanning = 1500 - (0.428 * 1500)

                                                          =  1500 - 723

Total number of people not exposed to indoor tanning   = 777 people

                                                       

a. Odds ratio = (a/b) / (d/c) = (696/411) / (777/723)

                                                = 1.69 / 1.07 = 1.58

b. Inasmuch the odds ratio is greater than 1, this means that higher odds of melanoma exist in people exposed to indoor tanning, than in those not exposed to indoor tanning.

7 0
3 years ago
The fertilization of ovules from Plant Q by pollen from Plant R results in the production of seeds. What percent of the genes in
blagie [28]

Answer:

The correct answer is - option A. 0%

Explanation:

The zygote formation or fertilization in flowering plants occurs by the fusion of pollen of one plant with the ovum of another plant of the same species normally. This process includes the exchange of an equal amount of the genetic contribution from both plants.

The egg cell of the mother is responsible for the mitochondria and chloroplast of the progeny so the percentage of chloroplast genes provided via Plant R is 0% as ovum and egg cell comes from only plant Q.

percentage of chloroplast gene inherited from R plant is a)0%

3 0
2 years ago
When you examine fluid that you have drawn from a blood vessel in someone's arm, you find that it is relatively high in carbon d
ziro4ka [17]

Answer:

The given blank can be filled with a venule.

Explanation:

A small blood vessel in the microcirculation, which connects the capillary beds to the veins is known as the venules. Various venules combine to form a vein. The walls of a venule are formed of three layers, that is, the inner endothelium formed of squamous endothelial cells, a middle layer of elastic and muscle tissue, and an external layer formed of fibrous connective tissue.  

The size of a venule ranges from 8 to 100 micrometers in diameter and are produced when capillaries come in close association. A venule refers to a small blood vessel that permits the deoxygenated blood high in carbon dioxide and waste products to return from capillary beds to the bigger blood vessels known as veins.  

4 0
3 years ago
When a germ cell undergoes meiosis, which event would MOST likely result in four aneuploid daughter
sveta [45]

Answer:

B. misalignment of the chromosomes during anaphase I

Explanation:

Aneuploidy refers to an error in the chromosomal number of a cell. This occurs when the chromosomes fail to separate equally into individual cells, a process called MEIOTIC NONDISJUNCTION. Meiotic disjunction can occur in either the anaphase stage of meiosis I or meiosis II, however, different outcomes are produced.

When chromosomes fail to separate at meiosis I, it results in two gametes that lack that particular chromosome (n-1) and two gametes with two copies of the chromosome (n+1). This means that the four daughter cells will have an incorrect number of chromosomes, hence, the misalignment of the chromosomes during anaphase I will result in four aneuploid daughter cells.

6 0
3 years ago
When skeletal muscle cells undergo anaerobic respiration, they become fatigued and painful. what is this caused by?
sineoko [7]
When the muscle or the skeletal muscle cells undergo anaerobic respiration, they become painful and fatingued, it is now known to be caused by build up of lactate. The skeletal muscle will be painful and fatigued and the caused of it will be because by build up of lactate.
3 0
3 years ago
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