Answer:
1 - Malaria
2- Typhoid fever and Tuberculosis
Explanation:
In case of malaria, the causal microorganism is Plasmodium falciparum, which target red blood cells of host. In humans who have defective sickle cell allele, have abnomral shaped red blood cells. So microorganism does not able to attach to abnormal shaped RBCs thus humans having sickle cell allele are more resistant to death caused by malaria.
In cystic fibrosis, mutation on that gene which encodes a protein known as cystic fibrosis transmembrane conductance regulator (CFTR).
Normally Salmonella typhi (bacteria responsible for typhoid fever) enters into intestinal cells by attaching with CFTR receptor. Carriers of cystic fibrosis mutant gene, have abnormal CFTR thus reduced rate of entry of bacteria into carriers.
Normally Mycobacterium tuberculosis (bacteria responsible for tuberculosis) adds sulfate in its cell walls. In carriers of cystic fibrosis, arylsulfatase B activity is reduced which incorporates sulfate. Thus reduced arylsulfatase activity makes bacteria unable to add sulfate in its cell walls thus decreases their virulence to carriers of cystic fibrosis.
Answer:
Fossil record, history of life as documented by fossils, the remains or imprints of organisms from earlier geological periods preserved in sedimentary rock. A brief treatment of the fossil record follows.
Explanation:
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Oftentimes UV light can cause the genetic code of an organism to mutate, leading to a variety of errors, some of which are not compatible with life.
UV light is considered to be a mutagen. What this means is that the exposure of cells to UV light often leads directly to a mutation in the genetic code of that cell. This correlation has been studied extensively and shown to affect the nucleotides of DNA, which are:
- A base (adenine)
- T base (thymine)
- G base (guanine)
- C base (cytosine)
The exposure to UV light causes the base nucleotides in the DNA of an organism to oxidize. This oxidization causes the base pairs to form dimers. Most often the dimer formed is of a <u>thymine base</u>. This can be thought of as the fusion between two thymine bases, which will alter the frame in which DNA is read and <u>cause all sorts of abnormalities</u>.
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