Answer:
Hypothalamus and anterior pituitary gland.
Explanation:
Lower levels of T3 and T4 in the blood or lower metabolic rate serve as signal and stimulate the release of thyrotropin-releasing hormone (TRH) from the hypothalamus. The TRH stimulates the anterior pituitary gland to release thyroid-stimulating hormone (TSH) which in turn makes the thyroid gland to release the thyroid hormones.
The elevated levels of thyroid hormones inhibit the release of TRH from the hypothalamus and that of TSH from the anterior pituitary gland.
Hence, the cells of hypothalamus and anterior pituitary gland would be inhibited by the binding of thyroid hormone to regulate the release of these hormones by a negative feedback mechanism.
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In nondisjunction, if members of a pair of homologous chromosomes do not move apart during meiosis I or sister chromatids fail to separate during meiosis II, this means one gamete receives 2 of the same kind of chromosome and i<span>f either one of these abnormal gametes unites with a normal one at fertilization, the zygote will also have an abnormal number of particular chromosomes; which is known as an aneuploidy.</span>
Answer:
These changes can be caused by environmental factors such as ultraviolet radiation from the sun, or can occur if an error is made as DNA copies itself during cell division. Acquired mutations in somatic cells (cells other than sperm and egg cells) cannot be passed to the next generation.
