<span>Tight junctions, at the site of a tight junction, cells are held tightly against each other by many individual groups of tight junction proteins called claudins, each of which interacts with a partner group on the opposite cell membrane. For example, the tight junctions between the epithelial cells lining your bladder prevent urine from leaking out into the extracellular space.</span>
The proteins are produced in the golgi apparatus. Then, they are transported through the microtubules inside the cell towards the cell membrane. Then, the proteins pass through the lipid bilayer of the membrane. of the membrane and move out of the cell.