The *heart* is the main organ of the circulatory system.
The circulatory system consists of three independent systems that work together: the heart (cardiovascular), lungs (pulmonary), and arteries, veins, coronary and portal vessels (systemic). The system is responsible for the flow of blood, nutrients, oxygen and other gases, and as well as hormones to and from cells.
<span>Enzyme and substrate bind using a lock-and-key mechanism. </span>
