<h2>How does a missense mutation affect the function of a protein?</h2>
A missense mutation will change the amino acid sequence. This may alter the function of the protein, usually negatively, but sometimes positively. This later case may be favored by evolution, as the change is heritable.
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The action potential generated through a threshold or suprathreshold stimulus on a neuron.
<h3>Where is the action potential generated?</h3>
The action potential (AP) originates thanks to a disturbance of the resting state of the cell membrane, with consequent flow of ions through the membrane and alteration of the ionic concentration in the intra and extracellular environments.
In this case, is a rapid change in the electrical potential of neuron membranes.
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Answer:
Because DNA molecules are extremely long.
Explanation:
DNA molecule is made up of only four types of nucleotides that are adenine, guanine, cytosine, and thymine. These four types of nucleotide encode all the information necessary for the formation and working of the entire organism because each DNA strand is as long as 2 meter which contains millions of base pairs.
The four nucleotides are arranged in the DNA strand with many different combinations which results in the formation of codons sequence that contains all the information about the cell. This long DNA is compressed several times to fit in the nucleus.
Answer:
Within the extracellular fluid, the major cation is sodium and the major anion is chloride.
Chloride is a major contributor to the osmotic pressure gradient between the ICF and ECF, and plays an important role in maintaining proper hydration. It functions to balance cations in the ECF, maintaining the electrical neutrality of this fluid.
Chloride is by large the major anion in the extracellular fluid.
Its concentration in blood plasma is around 98.00–107.00 (mM), in cerebrospinal fluid (CSF) around 118.00–132.00 (mM) and in urine around 110.00–250.00 (mM); while the concentrations of bicarbonate (HCO3-), the second most abundant anion in blood is 22.00–29.00 (mM).
Chloride is the predominant extracellular anion. Chloride is a major contributor to the osmotic pressure gradient between the ICF and ECF, and plays an important role in maintaining proper hydration. Chloride functions to balance cations in the ECF, maintaining the electrical neutrality of this fluid.
*ICF = intracellular fluid
ECF = extracellular fluid
