Answer:
Iris.
Explanation:
Eye is one of the most important sense organ of the body that helps to receive the light and also helps in the maintenance of the body equilibrium. The pupils regulate the amount of the light that enters in the eyes.
The Leslie has some eye problem and doctors use a sedative in her eyes. The sedative drug has the largest effect on the iris of the eye. The iris decides the color of the eye and also regulate the proper functioning of the pupil of eye.
Thus, the correct answer is iris.
Temperature and something else
L.S. is brought to the emergency department for management of acute mushroom poisoning. Her respirations are slow and shallow, and she is nonresponsive. She is admitted to the critical care unit to be closely monitored for the development of respiratory failure and renal failure, which often accompany mushroom poisoning. Her urine output is decreased to about 20 ml/hr. Her laboratory values are serum K+ = 5.7 mEq/L; arterial blood gases (ABGs): pH = 7.13, PaCO2 = 56 mm Hg, PaO2 = 89 mm Hg, HCO3- = 18 mEq/L.
1A. What is the most likely cause of L.S.’s potassium imbalance? Explain the role of the kidney in potassium excretion
Answer: L.S. is experiencing a intrarenal acute renal failure in the category of tubular necrosis (due to ingested mushroom toxins).
The kidneys helps to maintain the electrolyte concentrations by filtering electrolytes and water from blood, routing some to the blood, and excreting any excess into the urine.
Therefore, the kidneys help to maintain a balance between daily consumption and excretion of electrolytes and water.
Explanation:
Daily variations in potassium excretion are controlled mainly by changes in secretion in distal and collecting tubules.
• Maintaining potassium balance depends primarily on renal excretion which is determined by:
• the rate of potassium filtration
• the rate of potassium reabsorption by the tubules o the rate of potassium secretion by the tubules
i.e. About 65% the filtered potassium is reabsorbed the proximal tubule and another 25% to 30% in the ascending loop of Henle.
Answer:
True. The first trimester is the most crucial time for the development of the fetus.
Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
