Question

Chondroblasts ________. Select one: a. never lose their ability to divide b. within the cartilage divide and secrete new matrix c. are mature cartilage cells located in spaces called lacunae d. remain in compact bone even after the epiphyseal plate closes

Answer 1

Answer: b - Chondroblasts within the cartilage divide and secrete new matrix

Explanation: Chondroblasts are derived from two sources; mesenchymal cells within the center of chondrification and chondrogenic cells of the inner cellular layer of the perichondrium (coverings that lie over most cartilage).

At the chondrification centers, the cartilage forming cells (Chondroblasts) begin to secrete the components of extracellular matrix of cartilage. As the amount of matrix increases, the Chondroblasts become separated from each other and they are located in small cavity within the matrix called lacunae.

Concurrently, the cells differentiate into matured cartilage cells called chondrocytes.