T<span>he Plague of Justinian was a pandemic that afflicted the (Byzantine Empire), including Constantinople, in 541-542 CE. It is similar to that of the Black Death. It was nearly worldwide, striking central and south Asia, N. Africa, Arabia, and Europe.</span>
Answer:b
Explanation:
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Answer: D. Americas
Explanation:
The expansion of trade routes in the late Middle Ages and the beginning of the new century also led to new geographical and trade routes. The discovery of America was certainly the greatest event that took place from the mentioned epoch. Along with Europe, America has become the most important center in the world. The strengthening of trade led to new shopping centers, and some of these places were located in America. Thus Boston Harbor became the trading center of the world and the largest port in the world.