Explanation:
<u>anaerobic process that restores NAD+ supply
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Within cells, aerobic respiration may not occur due to several factors:
- - a lack of inorganic, final electron acceptors
- -incomplete or lack of a complete electron transport system
- -missing genes for enzymes within the Kreb's cycle
Thus, they utilize other means for the generation of energy in the form of ATP and to replenish NAD+ an oxidized form of NADH, the main electron carrier in glycolysis. Pyruvate is produced in the cytoplasm via glycolysis- it is also used as an electron acceptor in a process called fermentation.
Further Explanation:
overall: C6H12O6 (glucose) + 6 O2 → 6 CO2 + 6 H2O + ≈38 ATP
In all eukaryotic cells mitochondria are small cellular organelles bound by membranes, these make most of the chemical energy required for powering the biochemical reactions within the cell. This chemical energy is stored within the molecule ATP which is produced. Respiration in the mitochondria utilizes oxygen for the production of ATP in the Krebs’ or Citric acid cycle via the oxidization of pyruvate( through the process of glycolysis in the cytoplasm).
Oxidative phosphorylation describes a process in which the NADH and FADH2 made in previous steps of respiration process give up electrons in the electron transport chain these are converted it to their previous forms, NADH+ and FAD. Electrons continue to move down the chain the energy they release is used in pumping protons out of the matrix of the mitochondria.
This forms a gradient where there is a differential in the number of protons on either side of the membrane the protons flow or re-enter the matrix through the enzyme ATP synthase, which makes the energy storage molecules of ATP from the reduction of ADP. At the end of the electron transport, three molecules of oxygen accept electrons and protons to form molecules of water...
- Glycolysis: occurs in the cytoplasm 2 molecules of ATP are used to cleave glucose into 2 pyruvates, 4 ATP and 2 electron carrying NADH molecules. (2 ATP are utilized for a net ATP of 2)
- The Citric acid or Kreb's cycle: in the mitochondrial matrix- 6 molecules of CO2 are produced by combining oxygen and the carbon within pyruvate, 2 ATP oxygen molecules, 8 NADH and 2 FADH2.
- The electron transport chain, ETC: in the inner mitochondrial membrane, 34 ATP, electrons combine with H+ split from 10 NADH, 4 FADH2, renewing the number of electron acceptors and 3 oxygen; this forms 6 H2O, 10 NAD+, 4 FAD.
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Answer:
65% of oxygen
Explanation:
To name a few: Oxygen-65%, Carbon-18%, Hydrogen-10%
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
