As the years increase the deer population increases.
As the years increase the the wolf decreases
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
The answer is (A. A warm current flows along the coast.) Currents carry cold and warm water from place to place. It's an amazing phenomenon that scientists are still trying to fully figure out. Some think it's caused by wind, others think it's caused by the shifting of the tectonic plates, but one thing's for sure, currents are VITAL for this planets life.
Explanation:
During meiosis, sister chromosomes of a homologous pair separate into different cells during gamete formation . This mainly occurs in Metaphase I of meiosis where the homologous chromosomes line up the metaphase plate in their sets. Each chromosomes of a pair are then pulled to different poles of the cells separating them. Each of these chromosomes carries a set of alleles of a gene. Each cell/gamete, therefore, carried half the set of alleles of all genes compared to autosomal cells. There many combinations of these sets that can occur depending on the number of chromosomes the organism has.
These cells when combined with that of another parent during fertilization, form a zygote that grows and develops into a mature organism. The offspring will bear the characteristics of both parents because it inherits half a set of chromosomes from both parents.
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For more on meiosis check out;
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