Raising temperature generally speeds up a reaction, and lowering temperature slows down a reaction. However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. ... Extreme pH values can cause enzymes to denature.
The exons of the pre -mRNA contain the protein -coding regions.
Pre mRNA is the first made mRNA transcript and requires undergo many post transcriptional modifications for the formation of a mature mRNA.
The exons are the regions of the pre-mRNA that are found in the mature RNA, after the splicing of introns takes place.
RNA splicing is the process in which the non-coding segments of the RNA, which are known as introns, are removed by the help of small nuclear ribonucleoproteins. These SnRNPs make the spliceosome, which catalyzes the process of splicing.
After the introns are removed by the splicing process, the exons are covalently joined, which forms the mature mRNA.
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Answer:
Microchimerism is implicated in autoimmune diseases. This phenomenon, called microchimerism, is known as one that can provoke several autoimmune disorders, such as lupus and rheumatoid arthritis.
Explanation:
Chronic disease is a condition of human chimerism that shares similarities with some autoimmune diseases. Chimerism has been known to play a role in the pathogenesis of autoimmune diseases. Chimerism indicates the presence of cells from one individual in another individual. Chimeric cell injection causes lupus-like disease. Regarding all of this we can see that chimerism provokes autoimmune deseases.