Question

Which of the following experiments would provide the best supporting evidence that neutrophils are the cause of the reperfusion injury?A. Performing the ischemia/reperfusion experiment using animals whose B (antibody-producing) cells are depleted and examining whether the degree of tissue damage is reducedB. Performing the ischemia/reperfusion experiment using neutrophil-depleted animals and examining whether the degree of tissue damage is reducedC. Repeating the experiment with another antibody directed against the entire alpha/beta heterodimer, and examining whether the degree of tissue damage is reducedD. Repeating the experiment with another antibody directed against the beta subunit, and examining whether the degree of tissue damage is reduced

Answer 1

Answer:

Performing the ischemia/reperfusion experiment using neutrophil-depleted animals and examining whether the degree of tissue damage is reduced

Explanation:

Neutrophils are one of the important component of the white blood cells. Neutrophils has the ability to phagocytose the cell and these cells first reach at the time of parasitic infections.

In case of reperfusion experiment, the neutrophil cells can be used to obtain the best results. The variables that are used in the experiment can be tested and is limited in the absence and the presence of the neutrophil cells. The tissue damage can be diagnosed by this experiment.

Thus, the correct answer is option (B).