We humans are affecting the global food supply because of climate change. As you know the world is super polluted and threat of climate change is the collapse of food systems: Other threats — flooding, storms, forest fires — may be more sudden and severe in certain regions, but disruptions in food supply will affect virtually everyone.
Enzymes bind with chemical reactants called substrates
A genetic mutation. It's known as malformation. It can be caused by a trisomy in one of the alleles, or an affected gene.