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Yes, deletion of the possible control elements can cause reduction in reporter gene expression. Due to deletion of a control element, the activator cannot bind to the enhancer. This causes reduction in the gene expression.
Answer: Deletion of element no. 3 causes a reduction in reporter gene expression.
Answer:
A point mutation is a type of mutation in DNA or RNA, the cell’s genetic material.
Explanation:
DNA and RNA are made up of many nucleotides. There are five different molecules that can make up nitrogenous bases on nucleotides: cytosine, guanine, adenine, thymine (in DNA) and uracil (in RNA), abbreviated C, G, A, T, and U.
A protein kinase that is specific to the amino acids serine and threonine is known as a mitogen-activated protein kinase (MAPK or MAP kinase; also known as a serine/threonine-specific protein kinase).
<h3>Mitogen-activated protein kinase :</h3>
A small number of cell surface receptors can ultimately generate a large intracellular response due to activation of kinase cascades.
In order to trigger an appropriate physiological response, such as cellular proliferation, differentiation, development, inflammatory reactions, and death in mammalian cells, MAPK pathways relay, amplify, and integrate information from a variety of stimuli.
Tyrosine phosphorylation, specifically numerous tyrosines on each RTK in the dimer, is how cross-linking triggers the tyrosine kinase activity in these RTKs. The term "cross-phosphorylation" refers to this action.
The activation of a MAPKKKK or MAPKKK by stimulation of plasma membrane receptors is the initial stage of signal transduction. The MAPKKK then phosphorylates two serine or threonine residues in the S/T-X5-S/T (X is any amino acid) motif of its activation loop, activating a downstream MAPKK.
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Answer:
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If you were to draw a punnet square of two individuals with the genotypes Ss, there would be 1 box with ss, 2 boxes with Ss, and 1 box with SS.
The possible genotypes are SS, Ss, and ss.
The possible phenotypes are sufferers of sickle cell (ss) and non-sufferers (Ss and SS)