The answer is; glycolysis
This process converts glucose molecule to pyruvate. It is an oxygen-independent pathway, unlike the Krebs cycle. Glycolysis occurs in the cell cytoplasm while the Krebs cycle (aerobic pathway) occurs in the mitochondria. In the presence of oxygen, the product of glycolysis, i.e pyruvate, is fed to the Krebs cycle. If oxygen is unavailable the pyruvate is converted to lactate.
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
Answer:
Climate models can show the composition of the atmosphere in the future.
Explanation:
Climate models help predict how the average conditions will change in a region and they also serve as an extension of weather forecasting. They are quite broad and can make analysis and predictions over long time spans.
These models are generated from some set of mathematical principles with different data points numbering over a thousand. These large data points help increase the accuracy of the models.
Hii...so the answer is
The four layers are the external oblique, internal oblique, transverse abdominals.
hope u will like it.:)
