As a freshman myself, I say just prepare for the worst. Things in high school aren’t easy, nor will they get easier.
Answer:
Cheer them up! Try not to bring why they are depressed into whatever you are doing. If they don't want to or just want to be alone, just let them. Everbody wants to be alone sometimes.
The digestive enzyme that hydrolyzes lipids, acts as catalyst for the hydrolysis of lipid, aids emulsification of fat, and keeps tiny fat droplets suspended in the aqueous content of the gut is LIPASE. This enzyme is a subclass of esterases that breakdown fats to fatty acids and glycerol and other alcohols.