13 is bass but I’m not sure what 14 is
        
             
        
        
        
The circulatory system and respiratory system are protected by your skin, muscles, and ribs.
        
                    
             
        
        
        
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hi <3
changes in the enzyme's shape would decrease its ability to function as this would change the active site of the enzyme, meaning it is harder for it to carry out its job. 
this is why we try to keep enzymes in their optimum environmental conditions so they can function their best
hope this helps :)