DNA supercoiling means under or over winding of the DNA strand and basically is to become more condensed and more organized. Supercoiling is very important as it compacts the genetic code and as if that was not enough supercoiling also regulates and oversees the access the the genetic code.
On the Galapagos Islands, Darwin also saw several different types of finch, a different species on each island. ... Finches that ate small nuts and seeds had beaks for cracking nuts and seeds. Darwin noticed that fruit-eating finches had parrot-like beaks, and that finches that ate insects had narrow, prying beaks.
All of those can potentially harm the earth. Human activity is a cause of pollution, and pollution is the cause of acid rain to some extent.
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The Marburg virus wasn't mutating this early on, therefore the Coronavirus is much more deadlier and almost impossible to get a cure for, due to the rapid change in pathogens!