Answer:
The correct answers are option A. "Mutating histidine residue 274 of the citrate synthase enzyme to an alanine amino acid would likely eliminate or reduce the enzymatic activity of citrate synthase", B. "The histidine residue would hydrogen bond to acetyl-CoA throughout the reaction mechanism, stabilizing the enolate intermediate", and D. "Oxaloacetate would be repulsed from aspartic acid in the first step of the reaction mechanism".
Explanation:
Citrate cycle is comprised of a series of reactions used in aerobic organisms to release energy from different chemical species. In this cycle, the citrate synthase enzyme catalyzes the first reaction which is the formation of citrate by the condensation of acetyl-CoA and oxaloacetate. The enzymatic activity depends on the histidine residue 274, which acts as proton donor to the carbonyl oxygen of acetyl CoA stabilizing the enolate intermediate of citrate. Therefore, a mutating histidine residue 274 of the citrate synthase enzyme to an alanine amino acid would likely eliminate or reduce the enzymatic activity of citrate synthase, also oxaloacetate would be repulsed from aspartic acid in the first step of the reaction mechanism as a result of this modification.
Answer:
Extreme heat events can be dangerous to health – even fatal. These events result in increased hospital admissions for heat- related illness, as well as cardiovascular and respiratory disorders. Extreme heat events can trigger a variety of heat stress conditions, such as heat stroke.
Explanation:
Answer:
1. metaphase I
2. telophase II
3. anaphase I
4.prophase II
5. prophase I
6. anaphase II
7. telophase I
8. metaphase II
Explanation:
1. During _metaphase I________, pairs of homologous chromosomes align in the center of the cell.2. During _telophase II___, the separated chromatids elongate and (usually) cytokinesis occurs, formingfour genetically distinct haploid daughter cells.3. During _anaphase I_______, homologous chromosomes separate by moving with the spindle microtubulestoward the poles.4. During __prophase II______, a spindle apparatus forms and individual chromosomes (each composed ofsister chromatids) begin to move toward the center of the cell.5. During _prophase I_______, chiasmata form and crossing-over occurs.6. During _anaphase II_______, sister chromatids separate and move toward the poles.7. During __telophase I______, the separated chromosomes cluster at the poles of the spindle and cytokinesis occurs, forming two daughter cells, each with a haploid set of replicated chromosomes.8. During ___metaphase II_____, individual chromosomes (each composed of sister chromatids) align in the center of the cell.
The answer is C. Solar System, Milky Way, Universe
