When there is a cut on your skin, it gives bacteria and other organisms a gateway to enter directly into your bloodstream and could harm the body. By cleaning the wound, you prevent disease and infections from the bacteria.
The wood from Haiti’s forest is being used for:
C. Charcoal
Answer:
by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
The answer is mitochondrion
