The best statement here to build someone's self esteem would be a. I am really proud of you.
This is a positive statement and will help to increase someone's self esteem. All the other statements are negative and hurtful and would decrease someone's self esteem making them feel bad about themselves.
I am going to assume you are talking about emotion. If that is the case then it's better to let it all out, let the wall fall.
A non blood thinning pain reliever, like an opioid?
The answer is hydrolysis.<span />