1. As the cell size increases, the ratio of surface area to volume DECREASES
2. It depends on the unit of the ratio 6:1. If it is in cm−1, then it means that it is similar to a cell of size 1 cm^3, which is normally too big to get materials from the surface
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3. A Small cell has a large surface area/volume ratio and therefore can exchange molecules with it's external environment rapidly. So, Here cell with ratio 6:1 is smaller and have ability to better transportation across it's membrane as compared to other cell with ratio 3:1
very few M. tuberculosis in the standard nutrient cell cultures carry the rpoB gene mutation, but almost all of the M. tuberculosis in the cell cultures with rifampin carry the rpoB mutation