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Oxana [17]
3 years ago
13

Select the best answer for the question

Biology
1 answer:
Norma-Jean [14]3 years ago
6 0

Answer:

I think it is B. medium tell me if I am wrong

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The pKa for the side chain of histidine is 6.0. What is the ratio of the deprotonated imidazole side chain to the protonated sid
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Answer:

When the pKa is 6.0, we can determine the fraction of protonated H is by:

pH = pKa + log [A]/[HA]

Where

A = Deprotonated imidazole side

HA = Protonated side

Given, pH = 5.0

5 = 6 + log [A]/[HA]

log [A]/[HA] = -1 (take antilog of both side)

[A]/[HA] = 0.1

The ratio of the deprotonated imidazole side chain to the protonated side chain at pH 5.0 = 0.1

Given, pH = 7.5

7.5 = 6 + log [A]/[HA]

log [A]/[HA] = 1.5 (take antilog of both sides)

[A]/[HA] = 31.62

The ratio of the deprotonated imidazole side chain to the protonated side chain at pH 5.0 = 31.62

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