Pulse: a rhythmical throbbing of the arteries as blood is propelled through them, typically as felt in the wrists or neck.
Respiration:the action of breathing
It depends on the situation like if John breaks a glass of sues than he has to take responsibility but if sue breaks her glass then she has to take responsibility
The answer is : Tar
Tar is some sort of residual substance that we commonly found in tobacco products, which could cause the symptoms you've mentioned above
not only that, Tar is a highly carcinogenic substance, which mean that it generate high risk of cancer it get into our system