Question

What effect would you expect sarin to have on muscle function in individuals exposed to the nerve gas, and why? In your answer, discuss in detail how sarin would be expected to affect the neuromuscular junction, and how it would affect signaling and cytoskeletal events within affected muscle cells.
Drag the words on the bottom to the approproate blanks on the right to complete the sentences. Not all terms will be used.

Becauase reuptake of acetylcholine is inhibited, the muscle membrane at the neuromuscular junction will remain ______ for an abnormally long period, casuing the muscles to remain in a ______ state. The prolonged ______, in turn, would be propagated via the T tubule system to ________. The result would be prolonged release of calcium, resulting in sarcomere _______ voa the effects of calcium on _______.

Options: Extension, The troponin system, Relaxed, Depolarized, Contracted, Depolarization, Shortening, The sarcoplasmic reticulum, Polarization, Polarized.

Answer 1

Answer:

Becauase reuptake of acetylcholine is inhibited, the muscle membrane at the neuromuscular junction will remain depolarized for an abnormally long period, casuing the muscles to remain in a contracted state. The prolonged depolarization, in turn, would be propagated via the T tubule system to Sarcoplasmic reticulum. The result would be prolonged release of calcium, resulting in sarcomere shortening voa the effects of calcium on the Troponin system.