The last one, about coastal breezes
Sickle cell disease has a benefit in malaria infection because it makes the parasites easier to eliminate. This makes a person with sickle cell disease is more likely to survive the malaria infection, which found many in Africa.
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Sickle cell disease has a few drawbacks because it makes the red blood cells less durable, which lead to the destruction of more red blood cells. In normal condition(where malaria doesn't exist like in America), this gene will make the organism less likely to survive than those who don't have the gene.</span>
