Adenylate cyclases (ACs) are the membrane-bound glycoproteins that convert ATP to cAMP and pyrophosphate.
When activated by G-protein Gs, adenylate cyclases (ACs), which are membrane-bound glycoproteins, catalyze the synthesis of cAMP from ATP.
Different AC isoforms are widely expressed in various tissues that participate in regulatory systems in response to particular stimuli.
Humans have 9 different AC isoforms, with AC5 and AC6 thought to be particularly important for cardiac activities.
Nitric oxide has an impact on the activity of AC6, hence the protein's nitrosylation may control how it works. However, little is known about the structural variables that affect nitrosylation in ACs and how they relate to G's.
We predict the cysteines that are prone to nitrosylation using this 3D model, and we use virtual ligand screening to find potential new AC6 ligands.
According to our model, the AC-Gs interface's Cys174 in G's and Cys1004 in AC6 (subunit C2) are two potential residues that could experience reversible nitrosylation.
Learn more about glycoproteins here brainly.com/question/9507947
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The answers are A, B, & C. Steroid hormones have a
longer half-life than peptide hormones because steroid hormones ride on carrier
proteins in the blood. In other words, they
are bound to protein carriers that transport molecules across the membrane. They can also be stored temporarily in the adipose
tissue. And also, steroid hormones are sent to the nucleus where it regulates transcription
while peptides don’t require this process. This is the reason why the effects of
steroid hormones are exerted more slowly than peptides.
Answer:
early all of the hydrogen consumed in the United States is used by industry for refining petroleum, treating metals, producing fertilizer, and processing foods. U.S. petroleum refineries use hydrogen to lower the sulfur content of fuels.
Explanation:
Gan đóng vai trò trung tâm trong mọi quá trình trao đổi chất trong cơ thể. Trong quá trình chuyển hóa chất béo, các tế bào gan phân hủy chất béo và tạo ra năng lượng. Chúng cũng sản xuất khoảng 800 đến 1.000 ml mật mỗi ngày.
