Answer:
Myelinated Axons; leak channels are insulated by myelin leading to less loss of current flow and better conduction velocity. Ion channels omly located at nodes of ranvier; thus signal has sultatory conduction along myelin sheaths and jumps and move much quicker
Demyelinating diseases; along locations where myelin sheaths once was current links occur and conduction slows, the signal cannot make it very far because it looses energy as it travels through the axon
Unmyelinated axon; Ion channels are sequentially placed all along axons; thus it takes longer to send signal down axon. the energy isn't leaked out, it still contains the same signal but it is simply slower. distance between voltage gated channels needs to be small enough so local current flow can depolarize the membrane.
N/B; Harder to generate action potential in demyelinating disease
axon diameter( bigger diameter= less resistance= faster current).
Answer:
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Before designing a screening test, You should determine the people who are going to take the test, you should determine what the screening test would consist or contain and lastly how are the takers going to take on the test.
