Multiple Sclerosis is a demyelinating disease affecting axons in the<u>CNS </u>nervous system, in contrast to Guillain Barre Syndrome, which strips the myelin sheath from axons in the<u>PNS</u>nervous system.
Multiple sclerosis is an inflammatory disease in which our own immune system attacks our own nerve tissues and damages the central nervous system (brain and spinal cord).
Guillain-Barre syndrome is an autoimmune disease in which our peripheral nervous system (PNS) gets affected.