Question

The perioperative nurse is caring for a client who requires an umbilical hernia repair but who has a known family history of malignant hyperthermia. the client has been prescribed dantrolene 2.5 mg/kg iv one hour before surgery. the client weighs 121 lbs. the nurse reconstitutes a single-use vial as per the manufacture's instructions, yielding a solution with a concentration of 50 mg/ml. how many ml of the reconstituted dantrolene solution should the nurse add to the client's bag of intravenous fluid?

Answer 1

If the client weighs 121 lbs and the dantrolene doses is 2.5 mg/kg, the amount of dantrolene needed would be: 2.5mg/kg * 121lb *0.45 kg/lb= 137.2mg

If the dantrolene put on a solution with a concentration of 50 mg/ml, the volume of dantrolene needed would be: 137.2mg/ (50mg/ml)= 2.744ml