2. In the citric acid cycle, malate is oxidized to oxaloacetate by the enzyme malate dehydrogenase, which uses NAD+ as an electr
on acceptor. In cells, the ratio of [NAD+]/[NADH] is kept very high. Given the following standard reduction potentials, explain why it is so important for cells to maintain this ratio. Justify your answer with words, equations and diagrams.
NAD+ act both as coenzyme as well as electron acceptor compound and get reduced to NADH by accepting electron.
Explanation:
NAD+ act as co enzyme of various biological catalyst such as malate dehydrogenase, isocitrate dehydrogenase etc.
NAD+ can act as co enzyme only in its oxidized form but not in its reduced form called NADH.
Many reaction needs NAD+ to occur such as conversion of glyceraldehyde 3 phosphate to 1,3 bisphosphoglycerate, malate to oxaloacetate.
That"s why NAD+/NADH ratio is kept very high because if this ratio bychance get low then it will hamper the normal redox potential of NAD+/NADH.As a result many biochemical reaction will not take place.
Answer: because mammals have more complex biological structures; limb regeneration would require sophisticated controls to ensure that limbs and organs don’t grow out of control.
False because the third line of defense is specific by identifying the foreign antigen and activating the antibodies that can bind to the invaders and eliminating the spread
