The combined gas law states that the pressure of a gas is inversely related to the volume and directly related to the temperature. If temperature is held constant, the equation is reduced to Boyle's law. Therefore, if you decrease the pressure of a fixed amount of gas, its volume will increase.
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The answer is loss of muscle tissue. When you lose weight, you lose fat but if you
continue to lose weight and the fat has been lost then and you would start losing
muscle tissue. This gives the person a
gaunt-like appearance especially when he or she overdoes it.