You may be referring to the cytoplasm here. That is the "filling" within the cell. But if you are looking for specific transport of proteins, the ER folds proteins and then transport vesicles move them to the Golgi.
The blood flows through the vessels of the heart to keep it going
The expression or comment "Brain Freeze" means that the roof of your mouth is getting so cold that its affecting some of the nerves in your brain making it feel like a brain freeze.