I think a frameshift mutation that occurs very early in a protein sequence would have an effect on the structure of the protein such that the primary, secondary, and tertiary structures would be altered. A frameshift mutation occurs when a protein is drastically altered because of an insertion or a deletion. Insertions and deletions cause a change in the length of a gene, which causes a shift in the codon reading frame.
True due to the hormones that act upon the kidneys Two examples being Antidiuretic Hormone (ADH) and Aldosterone
ADH increases water permeability of the kidney tubules and Aldosterone decreases the Sodium in the urine and increases the Potassium.
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The answer is Liver disease