A chromosomally XY fetus has a completely functional SRY gene and develops fully functional testes that produce both testosteron
e and MIS; however, the fetus also has complete androgen insensitivity syndrome. What INTERNAL reproductive organs, aside from the testes, will this fetus develop?
Neither the Wolffian ducts nor the Mullerian ducts will develop
Explanation:
SRY gene is the gene is located on the Y chromosome and it is responsible for the development of testes.
MIS is Anti-Müllerian hormone which has the role to prevent the development of Müllerian ducts (they develop into female internal genitalia).
Androgen insensitivity syndrome is a disorder characterized by unfunctional androgen receptors. If androgen receptors are not working properly, the Wolffian ducts (they develop male internal organs) will not develop.
So, with MIS and withandrogen insensitivity syndrome, this fetus will not develop neither the Wolffian ducts nor the Mullerian ducts.
