The role of spindle fibers is to form protein that separates genetic material inside a cell.
Answer:
The answer is reciprocal chromosomal translocation
Explanation:
The Philadelphia chromosome (Ph) is the truncated chromosome 22 generated by the reciprocal translocation t(9;22)(q34;q11) and was first identified in 1960 in a patient with CML [3]. Translocation of the proto-oncogene tyrosine-protein kinase (ABL1) gene located on chromosome 9 to the breakpoint cluster region (BCR) gene located on chromosome 22 results in a BCR-ABL1 fusion gene on the Ph [4, 5]. Three BCR-ABL1 fusion gene hybrids encode BCR-ABL1 protein isoforms p210, p190, and p230, which have persistently enhanced tyrosine kinase (TK) activity. These aberrantly activated kinases disturb downstream signaling pathways, causing enhanced proliferation, differentiation arrest, and resistance to cell death [6, 7]. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 protein are the most successful targeted therapy for Ph-positive leukemia.
Fungi were classified in the kingdom Plantae because they are
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The biome that exist closest to the Earth's poles are descibed as polar
Answer:
Explanation:
Deoxyribonucleic acid is said to contain instruction for species characteristics because it carries the information that characterize an individual.
DNA are made up of Nitrogenous bases that are unique codes specify by an individual and no two person has the same the DNA.
Genes are genetic information or instruction that specify an individual. it is located in the chromosome in the nucleus. DNA contains gene which helps to make molecules called proteins. It is the basis of all inheritance and the expression of the gene is what produces the phenotype that is visible.
