Need the actual question ?
1. Without treatment, could potentially lead to death since 610,000 people die of heart disease every year.
2. You might have a heart attack. This is something that cannot be taken likely. And sometimes it cannot be treated with surgery.
The answer is C. Targeting a particular area for improvement
Specificity principle stated that whatever you do in the gym, should be relevant to your desired outcome
For example, if you are a rowing athlete, it should be best if you focus on upper body training more than lower body because you need your upper body strength more than you need the lower
It depends on how fit/active they are but there is no set amount I would say at least 10