It was determined from chemical analysis and observations by the EPA in the 1970's that the Love Canal in New York is considered to have "contaminated with toxic chemicals." Due to these, the canal was furthermore restricted to any human activities taking place due to the hazards it would produce.
There are many of them but the most common are:
1.) Photosynthesis
2.) Solar Energy
3.)Thermochemical Reactions
Schools in the United States started integrating in the 1950's as a direct result of the Brown v Board of Education Supreme Court ruling.
It would have to be the first since the British gave that land to America after the Revolutionary war. So they left that Native American to the Patriots.