New medications have more strict process to receive an approval from FDA compared to new dietary supplements which, some doesn't even need FDA's approval to be released in the market. Dietary supplements include in their labels "No approved therapeutic claims" to save them from legal responsibilities. During the titration, the repeated trials for the supplement varies from the medication is maybe because of less stability preservation of the supplement which caused it to degrade.
You can try to put your self into a calm mode and just relax and breath Hope this helps :)
The late stage is where the body and the mind start to fail. It could take weeks or maybe years to get to this stage.
