A systematic review and meta-analysis of empirical studies were arranged in order to appraise the relationship between sickle cell disease in pregnancy and adverse maternal and perinatal outcomes.
<h3>What is Sickle cell disease?</h3>
Sickle cell disease may be defined as a type of inherited disease in which the red blood cells of an individual possess an abnormal crescent shape with abnormal functions as well.
Eligibility criteria included empirical studies that significantly reported maternal and perinatal health conclusions in pregnant women with sickle cell disease hostile to a comparative group of pregnant women unaccompanied by sickle cell disease.
The standard of pregnancies in women with HbSS genotype, compared with women without sickle cell disease and was at an enhanced threat of maternal mortality.
Therefore, the systematic review and meta-analysis of sickle cell disease are well described above.
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