Straightforward, dependable core facility HLA tissue typing service
Using state of the art genotyping technologies as used in HLA typing for organ transplantation
We work with genomic DNA, Saliva, Whole Blood, or Cryopreserved cells
Detailed results typically sent in 3 weeks
typeHLA Tissue Typing Service Overview
Typing technology options
New Next Generation Sequencing (NGS)
PCR-SSOP using Luminex®
(previously called Tier 1)
HLA Class I loci available
A, B and C
(whole Class I panel reported)
A, B, C
(can be ordered individually)
HLA Class II loci available
DRB1, DPB1 and DQB1
(whole Class II panel reported)
DRB1, DRB3,4,5, DPA1*, DPB1, DQA1*, DQB1
(can be ordered individually)
Resolution of typing data
Fully resolved 4 digit (allelic level) typing with no degeneracy for all samples
4 digit (allelic level) typing but with some degeneracy
Features / Restrictions
Only available for ordering whole Class I panel (3 loci) or whole Cass II panel (3 loci) or whole Class I and Class II panel (6 loci)
Can be ordered for each locus individually
Turnaround time (approximate)
3 weeks
Sample formats accepted
gDNA, Cryopreserved PBMCs/other Cells, Blood, Saliva
Report format
Electronic format (PDF, XLS) via secure webserver
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Answer:
To facilitate DNA replication
Explanation:
The chromosomes must condense as to allow for DNA to replicate within the nucleus
Answer:
Answer: 2
Explanation:
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Answer 2
