What can be the problems encountered while using magnesium stearate as a lubricant with poorly soluble drug in hard gelatin caps

Question

3 years ago

15

ules?

1 answer:

Flauer [41] · Answer 1 · 2022-04-21T15:00:54+03:00

Answer:

The answer is explained below:

Explanation:

Magnesium stearate is primarily used as a lubricant and as anti-adherent and glidant. This occurs as plate-like crystals staked like a deck of cards.

The use of magnesium stearate causes compression and dissolution problems.

And because stearates are alkaline in reaction, it can not be used with some acidic drugs.