You get it very early, around 4 or 5 i believe.Its obvious because i hav personally been to a hospital for children with cancer, and the earliest i see there are 4 and 5 which means there must be the first check up at that time. need anything, tag me :)<span />
The answers would be: change the position very slowly, counting the pulse before medication and fatigue and wild weakness will be the common side affects. I hope this helps!